Share Why do so many people jenyne butterfly develop obesity and type 2 diabetes? According to stud

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Share Why do so many people jenyne butterfly develop obesity and type 2 diabetes? According to studies of the brain and neuroscience research in diseases of metabolism is omitted main feature of the brain - metaphorically - his selfishness (in English: "selfishness").
Of all the organs in the human brain so-called egocentric (Selfish Brain) 1 consumes the most energy in the form of glucose - namely 130g a day, which he derives firstly from the body. But what happens when the brain can not deliver enough energy from the body? Could obesity and type 2 diabetes are the bailouts of the brain? Principles and laws of the supplying chains Evidence for this view comes from the recent publication, 2 using the principles and laws of the supplying chain known logistics and economics, to describe just the central and peripheral energy jenyne butterfly metabolism. Applying the methods of economic analysis to the data on energy metabolism, has been shown successfully that supply difficulties in supplying the brain to chain it appears "jam" which is manifested in the form of filling is fat deposits. Circuit supplying the brain - the central nervous system as an end user - describes the energy flows from the farthest to the nearest environment of the body to the brain (Fig.). This chain is branched, i.e., it is possible to store energy in the side stores, such as muscle and adipose tissue.
Push and Pull components offering - delivering basic principle of the logistics supply chain is that the flow in them is determined by the proposer (component Push) and receiving (component Pull). In other words, the flows are regulated by supply and demand. Streams transport energy in various forms. Insufficient reception (Pull) of the brain during diabetes mellitus in the delivery chain of the human brain has been found to retain its healthy organism systemic energy homeostasis through enough acceptance (Brain-Pull) - i.e. the brain's ability to require enough energy from the body - and that the basis of obesity is insufficient intake Brain-Pull. Brain implement effective mechanisms for active body requires energy. There are two mechanisms of Brain-Pull: jenyne butterfly on the one hand if necessary, astrocytes, supplying jenyne butterfly cells to neurons require glucose from the bloodstream across the blood-brain barrier. The other neurons of the ventromedial jenyne butterfly hypothalamus jenyne butterfly issue orders that transmit energy flows in the body to the brain. Neurons activate the sympathetic nervous system and thus block the insulin secretion from beta cells. Thus this Brain-Pull-mechanism limiting insulin-dependent glucose uptake in GLUT4 in muscle and adipose tissue, while preserving insulin-dependent glucose uptake into the brain through jenyne butterfly GLUT1. jenyne butterfly Thus, circulating the first place is available to the brain. Apart from the mechanisms Brain-Pull exist Body-Pull, ie mechanisms of food intake: neurons of the lateral hypothalamus require jenyne butterfly input from the environment and initiate ingestion jenyne butterfly of food. Brain given only 1% or nothing has been shown that the effective mechanism of Brain-Pull is particularly significant in the case of a shortage of food in order to maintain brain and peripheral energy homeostasis. Two long-established experimental findings can now be explained, indicating that exhaustion all organs lose up to 40% by weight, while the brain loses only 1% or nothing. 3 What happens if the mechanisms of Brain-Pull jenyne butterfly does not work effectively? This threatens the brain supply. Metabolic emergency that compensates similar problem jenyne butterfly is the increase in food intake. This results in an adequate supply of glucose to the brain - but as side effect appears accumulation in the supply chain: in adipose tissue jenyne butterfly accumulates energy and appears jenyne butterfly obese. Energy accumulates in blood vessels and develop type 2 diabetes. 2 Emergency plans of the mind in terms of the study of brain metabolism zatl